08 June 2019

Saturday at American Society of Nutrition Conference 2019

My livestream from Saturday at the American Society of Nutrition conference 2019 in Baltimore. Today I sat in on many fascinating microbiome sessions.

hey welcome to nourish Ville I'm dr.

Laura and I'm here at the American Society of nutrition conference in Baltimore today is Saturday and the second day of the conference and I learned so many exciting things today I'm just gonna focus on stuff that I learned in the microbiome sessions today on but there was really so much I learned so the first thing that I learned in one of the microbiome sessions was looking at how we need to take the microbiome into consideration and how personalized it is when looking at different types of diets so in this particular study they were looking at how the different types of micro biomes would predict how well an individual responded to a weight loss that it so if you had one type of bacteria that was really predominating that would mean you wouldn't respond very well to this weight loss diet versus that you had a different community of microbes living in your dock then you would respond really well to that weight loss diet so I thought that was really interesting and another dimension to add to this whole personalized nutrition area another topic that I thought was really interesting was looking at studies

comparing a low fiber or no fiber diet to a high fiber diet a lot of types of fibers can't be digested by the human but they can be digested by the microbes so the more might the more fiber that you eat in your diet the more of these fiber loving microbes that you'll get in your gut now if you end up eating a diet that doesn't have very much fiber in it then some of those fiber loving microbes are gonna disappear but you're still gonna have a lot of microbes in your gut and those microbes have to eat something and so sometimes these microbes will start eating the carbohydrates that are in the mucous lining of your gut now I know it may sound kind of gross that we have mucus in our gut but it's actually really important for a healthy gut to have a nice thick layer of mucus that helps to separate what's inside your gut from getting inside of your body and so what these studies found these studies were in mice but they were showing that when they fed the mites the no fiber diet that all the sudden they had spike in these mucus loving microbes and those mucus loving microbes they eat away the lining and so that the mucus became really really Hin and then these

mice they ended up being really susceptible to getting infections because other types of pathogenic bacteria could get into inside their body body through the guts through this impaired mucous lining really easily so I thought that was really interesting and it'd be interesting to kind of put that in the context of humans and thinking about how important it is to eat a high fiber diet in humans that you're nourishing those good love those good microbes and not relying on the microbes eating your mucus in order to survive so I thought that was really interesting number three I listen to a really interesting study comparing how looking at how the microbiome changes when you're on a ketogenic diet so this was a new study that's about to be published but there are some really major changes in the microbiome when you go to eating a ketogenic diet that is you know 80% fat and very very low in carbohydrates of ever very low in fiber and then the last thing that was microbiome related I thought was fascinating today was looking at breast milk human breast milk another one of my favorite body fluids to research and so

this some of this research was really yet the whole idea that it's really energy intensive for a mother to produce breast milk and one of the compounds that's in breast milk are it's this type of carbohydrate they're called human milk oligosaccharides so just kind of HMOs just a fancy name for these types of carbohydrates that are found in human breast milk now the infant baby can't digest these HMOs so you would ask the question like why are they there why would they be in breast milk if breast milk has evolved to be the perfect nutrition for an infant baby but it turns out that these HMOs can be digested by microbes and so the fact that these HMOs are in the human breast milk that is helping develop the infant's microbiome to go in a particular direction so we've known for a while that there are pretty big differences between the micro biomes of formula-fed infants verses and breastfed infants but this is one of the big reasons is because the breastfed infants will develop a microbiome with lots of microbes that love eating those HMOs and then in turn when these microbes st. chats the HMOs they poop out beneficial

chemicals for the infant I thought that was really fascinating as well so so many things going on here they're really exciting and I will report back tomorrow on what I learned then bye got the science tastes like [Music]