17 August 2016

Grow New Brain Cells with Taurine, Improve a Congestive Heart and Metabolic Syndrome

Evidence that Taurine Grows New Brain Cells and Awakens "Hibernating" Stem Cells, Improves Congestive Heart Failure, and Helps Metabolic Syndrome, ...

from the Life Extension Foundation 2015

grow new brain cells with taurine for years scientists believe brain shrinkage was inevitable and irreversible cutting-edge research has shown that brain cells can regenerate an amino acid called taurine plays an important role in creating new brain cells researchers found that taurine increased the growth of brain cells by activating sleeping stem cells taurine also increased the survival of new neurons resulting in an increase in adult brain cell creation recent studies reveal that taurine has unique biochemical properties that promote new brain cell formation animal studies show that taurine triggers new brain cells to grow in the hippocampus the area of the brain most concerned with memory this can lead to dramatic improvements in cognition and recall low levels of taurine have been observed in patients with Parkinson's disease in addition to these impressive brain benefits taurine also boosts cardiac function and reduces arterial stiffness as well as reducing the negative impacts of metabolic syndrome in fact taurine supplementation added to the drug metformin has been shown to offer

tremendous reductions in tissue damage taurine levels fall significantly with age leaving the brain heart kidneys and other tissues deprived of this vital healing compound one capable of rescuing dying cells and restoring cellular communication experts are beginning to recognize that with age many can experience a taurine deficiency that is a real and fundamental threat to health the great news is that taurine is a super low-cost supplement meaning everyone can benefit from its potential to slow and reverse degenerative processes for years scientists believe that brain shrinkage or atrophy was an unstoppable degenerative process new research reveals this loss of brain matter is partially caused by reversible processes this knowledge opens the door to a new paradigm one that aims to restore brain structure and function as opposed to simply treating the symptoms one of the chief requirements for growing fresh brain cells is a little-known amino acid called taurine taurine has a surprising number of critical actions concerning how cells protect and renew themselves because touring levels decline with age older

adults are unable to maintain the level of new brain cell formation required to preserve their youthful responses to toxic and metabolic insults this taurine deficiency may lie at the heart of some of our most dreaded brain disorders studies show that restoring content in brain cells can reverse these trends and rejuvenate brain structure and function animal studies show that taurine triggers new brain cells to grow in the hippocampus a brain region centrally involved in memory a study published in the journal stem cell research found that taurine supplementation in middle-aged mice increase the growth of new cells and regions of the brain associated with learning and memory it accomplished this by activating hibernating stem cells that were then capable of maturing into several different kinds of cells in fact one study showed that when human neural precursor cells the early stage neurons and supporting cells in the brain were cultured with taurine it produced significantly more brain cells demonstrating how taurine stimulates stem like cells to differentiate into functioning brain cells in animals

taurine deficiency impairs brain growth by delaying normal neuronal development lab studies show that torreón can reverse this problem when taurine deficient brain cells are grown in culture and then taurine is added it results in a sharp increase in the development of new cells this is attributed to multiple mechanisms of action including approved mitochondrial function activation of genes required for normal proliferation survival and energy functioning and blocking chemical signals that inhibit neuronal cell regeneration in addition to promoting the growth of new brain cells taurine enhances neurites which are tiny projections that help brain cells to communicate with each other near i'ts maximize connect between those cells along which chemical impulses flow to support memory cognition feeling and thinking over time chemical stresses and toxins can damage these neurites contributing to slower cognition in older people a lab study revealed that taurine restores normal neuron growth and nerves exposed to toxic chemicals largely through its protective effects against chemical

stresses the findings at Orion can genuinely rejuvenate damaged brains are truly revolutionary and are beginning to change the way scientists and neurologists are thinking about age and trauma related brain dem a brain changes to specific conditions taurine has been shown to help benefit our Parkinson's disease and depression human studies show that taurine plasma levels are reduced in patients with parkinson's disease suggesting both the potential contribution to the disease and a possible treatment this problem is compounded by the fact that standard treatment of Parkinson's symptoms involves the drug levodopa which may further deplete taurine this makes it particularly important for Parkinson's patients to supplement with this versatile amino acid supplementing with taurine is also important for those suffering from depression depression is particularly prevalent in diabetics indeed there's a strong school of thought that chronic blood sugar elevations are involved in depression and neurodegenerative disorders such as Alzheimer's disease intriguingly taurine

supplementation in diabetic rats has been shown to improve depressive like behaviors in addition supplementation improved the diabetes damaged neurotransmitter function which helped lead to improved short-term memory heart disease remains the leading cause of death in u.s. adults a recent study in mice has for the first time suggested that taurine might prolong lifespan by improving heart muscle function the study used mice genetically engineered to be profoundly taurine deficient a state that causes premature aging and severe heart problems eventually resulting in early death painstaking work and other animal models revealed white Orion deficiency leads to these severe effects taurine deficiency disrupts the electron transport chain which reduces the amount of energy rich ATP available for heart cells to support their contractions leading to decreased pumping ability of the heart that fundamental finding that low touring levels contribute to or exacerbate poor heart muscle function is now being corroborated by lab and animal studies demonstrating improvements in heart or blood vessel performance poor or

unregulated control of arterial smooth muscle is a major contributor to high blood pressure and resulting cardiovascular disease fortunately taurine is known to have blood pressure reducing and heart muscle protecting effects in a lab study human artery segments were immersed in a chemical bath that induced contractions similar to those that occur during an angina episode or heart attack the addition of taurine to the bath resulted in relaxation of the artery animal and lab studies also show the taurine supplementation can mitigate ischemia reperfusion injury a major cause of long-term heart failure and further dysfunction this type of injury occurs when there is a loss of blood flow to the heart muscle called ischemia followed by the restoration of blood flow called repre both processes can lead to an energy crisis and high amounts of reactive chemicals ischemia reperfusion injury is severely exacerbated by high sugar intake and diabetes because of negative effects on nervous system signals taurine supplementation can abolish those aberrant signals and improve

arterial blood pressure following such an injury human studies are demonstrating the impact of tureens cardiovascular effects large epidemiological studies show that deficiencies in taurine are associated with an increase in cardiovascular risk factors for example when compared to people with the highest taurine levels those with the lowest levels had a 184 percent increase in the risk of obesity a 22 percent increase in the risk of hypertension and a 120 percent increase in the risk of elevated cholesterol while the risk of taurine deficiency is great encouraging studies show that supplementation with taurine can reduce risk factors for heart disease and in fact intervention studies are now showing that supplementation can rectify heart muscle energy deficiency to the point of improving clinical outcomes one of the best examples of this is a Russian study on patients undergoing heart valve replacement and coronary bypass surgery both of which are huge thieves of cardiac muscle energy this study showed that supplementation with taurine resulted in improved heart pumping action reducing

the size of the enlarged pumping chambers lower triglyceride levels and significantly improved quality of life these benefits may help to reduce the rates of sudden death after cardiac surgery which remain unacceptably high as is typical with many mainstream doctors if something costs virtually nothing as taurine does they overlooked its critical life-saving properties taurine has been shown to have protective effects against congestive heart failure a common energy-related complication in heart attack survivors cardiac surgery patients and people with hypertension or severe lung disease it results from an inability of the heart to pump sufficient blood to meet the demands of the body in a study published in the journal clinical cardiology patients with congestive heart failure took either a placebo or 2,000 milligrams of taurine three times a day compared to placebo recipients supplemented patients experience significant improvements in the severity of their heart failure and significant increases in measurements of the heart's ability to pump blood in addition none of the taurine

supplemented patients worsened during treatment while 29% of placebo subjects did in a similarly designed study heart failure patients who took 500 milligrams of taurine 3 times a day experienced increases in exercise time and distance and increased ability to utilize cardiac energy compared with placebo this is a graphic example of how taurine can affect heart muscle energy production making it more efficient and helping to energize tired heart muscle another study of heart failure patients showed that taurine supplementation 3 grams per day for 6 weeks resulted in significant changes in echocardiogram results which showed improvements in the pumping action of the left ventricle the chamber that pumps blood out to the entire body clearly ample blood taurine levels are required for proper heart functioning and this data was published by Life Extension decades ago based on what cardiologists in Japan had discovered when treating congestive heart failure patients with 3 grams of taurine per day let's now look at some ways at taurine can reduce the risk for developing

cardiovascular disease in the first place metabolic syndrome is the combination of central obesity high blood pressure insulin resistance borderline high blood sugar elevated triglyceride levels and low HDL cholesterol levels it is strongly associated with short and long term risks of cardiovascular and kidney disease diabetes cancer and death touring supplements have been found to be extremely effective in reducing harmful effects of metabolic syndrome while at the same time inducing changes that reduce the syndromes long-term impact on cardiovascular risk studies of diabetic and or obese mice and rats demonstrate the touring leads to consistent improvements in multiple components of metabolic syndrome including insulin secretion and sensitivity and glucose tolerance one study also showed that touring deficient mice develop kidney changes identical to those in human diabetic nephropathy the leading cause of end-stage kidney disease this suggests at taurine supplementation and metabolic syndrome patients might lower renal disease risk and in a remarkable pair of studies

taurine was shown to amplify the beneficial effects of metformin a naturally derived anti-diabetic drug with multiple health promoting effects in metabolic syndrome in the first study when rats were treated with both taurine and metformin they were better protected against chemical and metabolic stresses than when either was used alone for the second study the combination of taurine supplementation and metformin was found to provide the same pattern of protection as insulin against diabetes induced metabolic changes including preservation of renal function human studies demonstrated just how important taurine supplementation is for people with metabolic syndrome which exacerbates the age-related decline in touring levels compared with healthy people obese people have as much as a 41 percent reduction in touring levels compared with healthy controls while diabetics have a 30% reduction in touring levels the good news is that supplementing with taurine significantly reduces many of the risk factors faced by those with metabolic syndrome for example at doses of 3 grams per day for 8 weeks

a group of obese adults had significant 29% reductions in plasma markers of inflammation and 20% reduction in lipid peroxidation and when diabetics supplemented with 1.5 grams per day not only were their touring levels restored to normal but their platelet aggregation was reduced to levels seen in healthy controls and by the way platelet aggregation is elevated in diabetics which increases the risk for stroke or heart attack inducing blood clots this study also involved a laboratory test of platelet aggregation which showed that while taurine reduced aggregation in blood from diabetic patients it had no effect at all on blood from healthy controls this is a safety concern about virtually all prescription antiplatelet drugs in addition to the heart disease and stroke risk induced by aggressive platelet aggregation diabetics and non-diabetic people with chronically high normal blood sugar levels are at increased cardiovascular risk from physical stiffening of their arteries again taurine supplementation is able to reverse this dangerous state of affairs in a study published in diabetes and vascular disease research young adults

with type 1 diabetes and impaired endothelial functions supplemented with 500 milligrams of taurine three times a day after just two weeks their abnormal arterial stiffening and reactivity returned to levels found in controls since type 1 diabetes formerly known as juvenile onset or insulin dependent diabetes exposes its victims to much greater elevation in fluctuation in glucose levels even than those seen in type 2 which is adult onset diabetes seeing this dramatic effect in the more severe form of the disease is especially encouraging for the much larger population of type 2 diabetics in summary taurine a little-known amino acid can do the seemingly impossible and that is stimulate new brain cells to grow in adult brains this capability creates an entirely new paradigm for the ways we think about age-related cognitive decline and even major neurodegenerative diseases like Parkinson's and Alzheimer's taurine levels fall as we age leading your brains relatively unprotected taurine levels are low in people with age-related brain disorders animal studies reveal that supplementation can

not only restore youthful taurine levels but also improves deficits in memory and cognition taurine also has a fundamental connection with longevity particularly related to cardiovascular disorders animal studies demonstrate protection against heart disease with taurine supplementation and human studies show that supplementation produces dramatic improvements in heart and blood vessel function people with metabolic syndrome have lower touring levels and their healthy peers again touring supplementation drives down the detrimental effects of metabolic syndrome while inducing changes that reduce the syndromes long-term impact on cardiovascular risk a balanced supplement program should aim at restoring youthful levels of nutrients known to counteract the chemical stresses inflammatory changes and toxic exposures we experience through life the evidence for the amino acid taurine suggested it be included in such a regimen you've been listening to an article from The Life Extension Foundation magazine from 2015 this is brought to you by Scott health systems

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